In clinical trials, 8 out of 10 people achieved clear or almost clear skin at 4 months (16 weeks).
Your doctor has prescribed SKYRIZI for your moderate to severe plaque psoriasis (Ps).
You may have questions.
That’s not surprising. Moderate to severe plaque psoriasis is a complex condition. The more you know about your prescribed treatment plan, the better prepared you’ll be to follow it.
About SKYRIZI
Treating moderate to severe plaque psoriasis with SKYRIZI.
SKYRIZI may help you keep your skin clearer with 4 doses a year, after 2 starter doses.
SKYRIZI Clinical Trial Results
90% CLEARER SKIN ACHIEVED
SKYRIZI clinical trial patient. Your results may vary.
Each SKYRIZI dose is injected under the skin.
Starting SKYRIZI requires 2 starter doses, and maintenance is 1 dose every 12 weeks.
Each dose is 150mg/ml
SKYRIZI Complete Resources
Skyrizi Complete: Resources designed around you.
You are unique, and so is your treatment journey. That’s why Skyrizi Complete offers personalized, 1-to-1 support and resources.
The heart of Skyrizi Complete: Your dedicated Ambassador*
As a reminder, the Skyrizi Complete program can educate and support you every step of the way in your treatment. Your dedicated Nurse Ambassador can provide personalized, one-on-one support and is committed to answering your questions about SKYRIZI and helping you understand your treatment. If you are not currently connected to a Nurse Ambassador, you can call 1.866.SKYRIZI or visit skyrizi.com to get connected.
Skyrizi Complete will also help you:
Get supplemental injection training
if you and your doctor decide you may want to inject at home.
Find ways you may be able to save
such as with the Skyrizi Complete Savings Card.†
Navigate insurance
with the guidance of Insurance Specialists.
Understand your role
in the prescription process to make sure your SKYRIZI is there when you need it.
Your Ambassador
is always here to help you
Reach out to your Ambassador any time you have questions about SKYRIZI or Skyrizi Complete support and resources by calling 1.866.SKYRIZI (1.866.759.7494). Prefer to meet virtually? Ask your Ambassador if virtual visits are available.
*Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.
†Eligibility: Available to patients with commercial insurance coverage for SKYRIZI® (risankizumab-rzaa) who meet eligibility criteria. This co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offer subject to change or termination without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit SKYRIZISavingsCard.com or call 1.866.SKYRIZI for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit https://privacy.abbvie
Understanding Plaque Psoriasis
Understanding a complex condition.
The more you know about plaque psoriasis (Ps), the easier it may be to understand your condition. This can also help you explain your experience to others.
A chronic, inflammatory disease
Ps is a chronic condition, meaning symptoms may keep coming back and could last a long time.
Where it strikes
Ps can appear on any part of your body. It is typically found on elbows, knees, fingernails, lower back (trunk) and scalp.
A combination of causes
The exact cause of Ps is unknown, but it is believed to be caused by a combination of immune, genetic, and environmental factors.
Who is at Risk for Plaque Psoriasis?
A combination of factors.
Anyone can get moderate to severe plaque psoriasis (Ps), but there are risk factors that may increase your chances. Talk to your doctor to learn more about possible risk factors.
How Your Immune System Triggers Inflammation
The immune/inflammation connection.
Normally, the immune system protects your body from disease by attacking bacteria and viruses. But with plaque psoriasis (Ps), the immune system becomes overactive.
Use the slider to explore what's happening beneath the skin––in people with and without Ps.
- An imbalanced immune system involves excess proteins
- Excess proteins lead to chronic inflammation
- Skin cells multiply too rapidly
- Extra skin cells pile up to form plaques
Plaque Psoriasis Symptoms
Know the signs.
The signs and symptoms of moderate to severe plaque psoriasis may include what is shown below:
Click on the symptoms below to see what they look like.
How SKYRIZI Works
How SKYRIZI works in your body.
While the exact cause of plaque psoriasis in unknown, an overactive immune system could be a source.
Your body may produce too much of certain proteins.
IL-23 is one of several proteins that may contribute to excess inflammation in the body, which can lead to painful, red, itchy plaques on the skin.
SKYRIZI has been designed to work with your immune system, attaching to this IL-23 protein that can cause inflammation. By attaching to this protein, SKYRIZI helps reduce the inflammation inside the body that leads to plaques on the skin.
ADDITIONAL SAFETY INFORMATION
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about SKYRIZI®(risankizumab-rzaa)?
SKYRIZI may cause serious side effects, including infections. SKYRIZI is a prescription medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.
What is the most important information I should know about SKYRIZI® (risankizumab-rzaa)?
SKYRIZI may cause serious side effects, including:
- Serious allergic reactions: Stop using SKYRIZI and get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth,tongue, or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- itching
- Infections: SKYRIZI may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with SKYRIZI and may treat you for TB before you begin treatment with SKYRIZI if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with SKYRIZI.
Do not use SKYRIZI if you are allergic to risankizumab-rzaa or any of the ingredients in SKYRIZI.
Also, tell your doctor if you plan to or recently received a vaccine.
Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- muscle aches
- weight loss
- cough
- warm, red, or painful skin or sores on your body different from your psoriasis
- diarrhea or stomach pain
- shortness of breath
- blood in your mucus (phlegm)
- burning when you urinate or urinating more often than normal
Before using SKYRIZI, tell your healthcare provider about all of your medical conditions, including if you:
- have any of the conditions or symptoms listed in the section “What is the most important information I should know about SKYRIZI?”
- have an infection that does not go away or that keeps coming back.
- have TB or have been in close contact with someone with TB.
- have recently received or are scheduled to receive an immunization (vaccine). Medications that interact with the immune system may increase your risk of getting an infection after receiving live vaccines. You should avoid receiving live vaccines right before, during, or right after treatment with SKYRIZI. Tell your healthcare provider that you are taking SKYRIZI before receiving a vaccine.
- are pregnant or plan to become pregnant. It is not known if SKYRIZI can harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if SKYRIZI passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of SKYRIZI?
SKYRIZI may cause serious side effects. See “What is the most important information I should know about SKYRIZI?”
The most common side effects of SKYRIZI include upper respiratory infections, feeling tired, fungal skin infections, headache, and injection site reactions.
These are not all the possible side effects of SKYRIZI. Call your doctor for medical advice about side effects.
Use SKYRIZI exactly as your healthcare provider tells you to use it.
SKYRIZI is available in a 150 mg/mL prefilled syringe and pen.
Please see the Full Prescribing Information, including the Medication Guide, for SKYRIZI.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.